Guaianolides from Salvia nubicola (Lamiaceae)

Muhammad Shaiq Ali; Waqar Ahmed; Andrea Florence Armstrong; Syed Amir Ibrahim; Shakeel Ahmed; Masood Parvez

doi:10.1248/cpb.54.1235

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Guaianolides from Salvia nubicola (Lamiaceae)

Muhammad Shaiq Ali, Waqar Ahmed, Andrea Florence Armstrong, Syed Amir Ibrahim, Shakeel Ahmed, Masood Parvez

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Keywords: Salvia nubicola, Lamiaceae, guaianolide, 2D-NMR, X-ray

JOURNAL FREE ACCESS

2006 Volume 54 Issue 9 Pages 1235-1238

DOI https://doi.org/10.1248/cpb.54.1235

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Abstract

A new sesquiterpene-lactone (nubenolide) belonging to the guaianolide class along with its acetate (nubenolide acetate) and a dimer (bisnubenolide) have been isolated from Salvia nubicola collected from Quetta, Pakistan. Structures of all three new metabolites were elucidated with the aid of spectroscopic techniques including 2D-NMR. However, the structure of nubenolide was finally confirmed via single-crystal X-ray diffraction method.

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