New Diphenyl Ethers from the Insect Pathogenic Fungus Cordyceps sp. BCC 1861

Taridaporn Bunyapaiboonsri; Seangaroon Yoiprommarat; Kamolphan Intereya; Kanokarn Kocharin

doi:10.1248/cpb.55.304

Regular Articles

New Diphenyl Ethers from the Insect Pathogenic Fungus Cordyceps sp. BCC 1861

Taridaporn Bunyapaiboonsri, Seangaroon Yoiprommarat, Kamolphan Intereya, Kanokarn Kocharin

著者情報

キーワード: Cordyceps sp., diphenyl ether, phenyl ether glycoside

ジャーナルフリー

2007 年 55 巻 2 号 p. 304-307

DOI https://doi.org/10.1248/cpb.55.304

詳細

抄録

Two novel diphenyl ether glycosides and a new diphenyl ether, cordyol A—C (1—3), were isolated from the insect pathogenic fungus Cordyceps sp. BCC 1861. Structures of these compounds were elucidated by NMR and MS spectral analyses. Cordyol C (3) exhibited significant anti-HSV-1 activity with an IC₅₀ value of 1.3 μg/ml, and cytotoxic activity against BC and NCI-H187 cancer cell lines with IC₅₀ values of 8.65 and 3.72 μg/ml, respectively. Cordyol A (1) displayed weak antimycobacterial activity with a MIC value of 100 μg/ml.

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