Convallasaponin A, a New 5β-Spirostanol Triglycoside from the Rhizomes of Convallaria majalis

Taro Higano; Minpei Kuroda; Hiroshi Sakagami; Yoshihiro Mimaki

doi:10.1248/cpb.55.337

Notes

Convallasaponin A, a New 5β-Spirostanol Triglycoside from the Rhizomes of Convallaria majalis

Taro Higano, Minpei Kuroda, Hiroshi Sakagami, Yoshihiro Mimaki

著者情報

キーワード: Convallaria majalis L., Liliaceae, 5β-spirostanol triglycoside, convallasaponin A, cardenolide glycoside, cytotoxic activity

ジャーナルフリー

2007 年 55 巻 2 号 p. 337-339

DOI https://doi.org/10.1248/cpb.55.337

詳細

抄録

The rhizomes of Convallaria majalis have been analyzed for their steroidal glycoside constituents, resulting in the isolation of a new 5β-spirostanol triglycoside, named convallasaponin A, along with two known cardenolide glycosides and a known cholestane glycoside. The structure of convallasaponin A was determined on the basis of extensive spectroscopic analysis, including 2D NMR data, and the results of hydrolytic cleavage. The cardenolide glycosides showed tumor specific cytotoxic activity.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）