Preparation and Antibacterial Activity of Copper and Cobalt Complexes of 4-Chloro-3-nitrobenzoate with a Nitrogen Donor Ligand

Abstract

Copper and cobalt complexes with 4-chloro-3-nitrobenzoate (ClNBz) and the nitrogen ligands 1,3-diaminopropane (1,3-DAP) or o-phenylenediamine (o-PDA), were prepared and characterized. The complexes [Cu(ClNBz)₂(1,3-DAP)] (1), [Cu(ClNBz)(o-PDA)]Cl (2), [Co(ClNBz)₂(1,3-DAP)] (3) and [Co(ClNBz)₂(o-PDA)₂] (4) were characterized by FTIR, UV–Visible absorption, elemental analysis and thermal analysis. Complex [Cu(ClNBz)(o-PDA)]Cl (2) shows high antibacterial activity as indicated by its ability to inhibit the growth of Staphylococcus aureus, Enterococcus faecalis.