Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Four Novel Metabolites from Microbial Transformation of Curcumol by Cunninghamella blakesleana
Hui Zhang, Ning Kang, Feng Qiu, Ge-Xia Qu, Xin-Sheng Yao
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2007 年 55 巻 3 号 p. 451-454

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Further study on the microbial transformation of curcumol (1) by Cunninghamella blakesleana (AS3.970) led to the isolation of four novel metabolites. Their structures were elucidated as 3β-hydroxy curcumol (2), 12-hydroxy curcumol (3), 1α-hydroxy-10β,14-epoxy curcumol (4) and (2S,4S,5S,7S)-10-hydroxymethyl-7-isopropyl-2-methoxy-4-methyl-1-oxaspiro[4,6]undec-10-en-8-one (5) on the basis of spectral methods. All of them were characterized as new compounds.
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© 2007 The Pharmaceutical Society of Japan
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