Cowaniin, a C-Glucosidic Ellagitannin Dimer Linked through Catechin from Cowania mexicana

Hideyuki Ito; Masateru Miyake; Eisei Nishitani; Kyoko Miyashita; Morio Yoshimura; Takashi Yoshida; Midori Takasaki; Takao Konoshima; Mutsuo Kozuka; Tsutomu Hatano

doi:10.1248/cpb.55.492

Notes

Cowaniin, a C-Glucosidic Ellagitannin Dimer Linked through Catechin from Cowania mexicana

Hideyuki Ito, Masateru Miyake, Eisei Nishitani, Kyoko Miyashita, Morio Yoshimura, Takashi Yoshida, Midori Takasaki, Takao Konoshima, Mutsuo Kozuka, Tsutomu Hatano

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Keywords: Cowania mexicana, Rosaceae, cowaniin, complex tannin, C-glucosidic ellagitannin dimer, Epstein-Barr virus

JOURNAL FREE ACCESS

2007 Volume 55 Issue 3 Pages 492-494

DOI https://doi.org/10.1248/cpb.55.492

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Abstract

A new complex tannin, cowaniin (1) was isolated from the leaves and stems of Cowania mexicana (Rosaceae), and its structure was characterized as novel C-glucosidic tannin dimer linked through (+)-catechin on the basis of spectral and chemical evidence. The inhibitory effect on activation of the Epstein-Barr virus early antigen was assessed for cowaniin. Six known polyphenols and related compounds, including a nitrile glucoside, purshianin, were also characterized.

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