2007 Volume 55 Issue 4 Pages 675-678
Allergy-preventive activity was demonstrated for an extract of resins from Xanthorrhoea hastilis R. BR. in a search for allergy-preventive substances from natural sources. By bioassay-directed fractionation of this plant extract, a new flavanone, 3′,5′-dihydroxy-7,4′-dimethoxyflavanone (1), and two new chalcones, 3,5,2′-trihydroxy-4,4′-dimethoxychalcone (2) and 5,2′-dihydroxy-3,4,4′-trimethoxychalcone (3), were isolated together with five known compounds, 5′-hydroxy-7,3′,4′-trimethoxyflavanone (4), 3′-hydroxy-7,4′-dimethoxyflavanone (5), liquiritigenin 7-methyl ether (6), 4,2′-dihydroxy-4′-methoxychalcone (7) and sakuranetin (8). The structures of 1, 2 and 3 were elucidated by spectroscopic methods. All of these compounds showed allergy-preventive effects.
