Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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New Cytotoxic Cembranolides from the Soft Coral Lobophytum michaelae
Li-Tang WangShang-Kewi WangKeryea SoongChang-Yih Duh
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2007 Volume 55 Issue 5 Pages 766-770

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Abstract
Eleven new cytotoxic cembranolides, michaolides A—K (1—11), and crassolide (12) were isolated from the CH2Cl2 extract of the Formosan soft coral Lobophytum michaelae. Their structures were established by extensive spectral analysis. The cytotoxicity of the isolates against selected cancer cells was measured in vitro.
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© 2007 The Pharmaceutical Society of Japan
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