Preparation of Quinoline Hexose Analogs as Novel Chloroquine-Resistant Malaria Treatments (1). Synthesis of 4-Hydroxyquinoline-β-glucosides

Hiroshi Suzuki; Nagwa S. M. Aly; Yusuke Wataya; Hye-Sook Kim; Ikumi Tamai; Masaki Kita; Daisuke Uemura

doi:10.1248/cpb.55.821

Notes

Preparation of Quinoline Hexose Analogs as Novel Chloroquine-Resistant Malaria Treatments (1). Synthesis of 4-Hydroxyquinoline-β-glucosides

Hiroshi Suzuki, Nagwa S. M. Aly, Yusuke Wataya, Hye-Sook Kim, Ikumi Tamai, Masaki Kita, Daisuke Uemura

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Keywords: malaria, chloroquine-resistant malaria treatment, quinoline-glucosides

JOURNAL FREE ACCESS

2007 Volume 55 Issue 5 Pages 821-824

DOI https://doi.org/10.1248/cpb.55.821

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Abstract

Quinoline hexose analogs are expected to be useful as novel agents for treatment of chloroquine-resistant malaria. Here, we report preparation of 4-hydroxy quinoline-β-glucosides from anilines in 4 steps.

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