New Sesquiterpenes and Calebin Derivatives from Curcuma longa

抄録

One novel sesquiterpene with new skeleton, (6S)-2-methyl-6-(4-hydroxyphenyl-3-methyl)-2-hepten-4-one (1), two new bisabolane sesquiterpenes, (6S)-2-methyl-6-(4-hydroxyphenyl)-2-hepten-4-one (2), (6S)-2-methyl-6-(4-formylphenyl)-2-hepten-4-one (3), and two calebin derivatives, 4″-(4′′′-hydroxyphenyl-3′′′-methoxy)-2″-oxo-3″-butenyl-3-(4′-hydroxyphenyl)-propenoate (4) and 4″-(4′′′-hydroxyphenyl)-2″-oxo-3″-butenyl-3-(4′-hydroxyphenyl-3′-methoxy)-propenoate (5) were isolated along with five known bisabolane sesquiterpenes from Curcuma longa. 1—4 were new compounds and 5 was a new natural product. Their structures were established by spectral methods.