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Chemical and Pharmaceutical Bulletin
Vol. 56 (2008) No. 1 P 79-81




The direct conversion of α-hydroxy ketones and α-keto oximes into quinoxaline derivatives in the presence of a catalytic amount of ceric ammonium nitrate via metal-catalyzed aerobic oxidation followed by in situ trapping with aromatic 1,2-diamines in water as a green and efficient reaction media, is reported.

Copyright © 2008 The Pharmaceutical Society of Japan

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