Solution-Phase Parallel Synthesis of Novel 1,2,3,4-Tetrahydroisoquinolin-1-ones as Anticonvulsant Agents

Rosaria Gitto; Eleonora Francica; Giovambattista De Sarro; Francesca Scicchitano; Alba Chimirri

doi:10.1248/cpb.56.181

Notes

Solution-Phase Parallel Synthesis of Novel 1,2,3,4-Tetrahydroisoquinolin-1-ones as Anticonvulsant Agents

Rosaria Gitto, Eleonora Francica, Giovambattista De Sarro, Francesca Scicchitano, Alba Chimirri

著者情報

キーワード: solution-phase parallel synthesis, isoquinolinone, anticonvulsant agent

ジャーナルフリー

2008 年 56 巻 2 号 p. 181-184

DOI https://doi.org/10.1248/cpb.56.181

詳細

抄録

Following our previous studies in the field of anticonvulsant agents, we planned a one-pot solution-phase parallel synthesis (SPPS) of a small library of new 1,2,3,4-tetrahydroisoquinoline derivatives. The activity against audiogenic seizures in DBA/2 mice of the newly synthesized compounds has also been evaluated.

責任著者(Corresponding author)

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