Further Cytotoxic Sesquiterpene Lactones from Elephantopus mollis K<small>UNTH</small>

Turibio Kuiate Tabopda; Joseph Ngoupayo; Jiawei Liu; Muhammad Shaiq Ali; Shamsun Nahar Khan; Bonaventure Tchaleu Ngadjui; Bang Luu

doi:10.1248/cpb.56.231

Notes

Further Cytotoxic Sesquiterpene Lactones from Elephantopus mollis KUNTH

Turibio Kuiate Tabopda, Joseph Ngoupayo, Jiawei Liu, Muhammad Shaiq Ali, Shamsun Nahar Khan, Bonaventure Tchaleu Ngadjui, Bang Luu

著者情報

キーワード: neuroblastoma, sesquiterpene lactone, Elephantopus mollis

ジャーナルフリー

2008 年 56 巻 2 号 p. 231-233

DOI https://doi.org/10.1248/cpb.56.231

詳細

抄録

Three new sesquiterpene lactones, (4βH)-5α-hydroxy-8α-(2-methylbut-2-enoyloxy)-2-oxo-1(10),11(13)-guaiadien-12,6α-olide (1), (4βH)-8α-(2-methylbut-2-enoyloxy)-2-oxo-1(5),10(14),11(13)-guaiatrien-12,6α-olide (2) and 2,5-epoxy-2β-hydroxy-4α-methoxy-8α-(2-methylbut-2-enoyloxy)-4(15),10(14),11(13)-germacratrien-12,6α-olide (3), have been isolated from roots and stems of Elephantopus mollis together with two known sesquiterpene lactones (4, 5). The identification of the isolates was accomplished by spectroscopic methods. Compounds (1—5) exhibited significant cytotoxic activities against mouse neuroblastoma B104 cells.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）