Sulfonic Acid Functionalized Silica: An Efficient Heterogeneous Catalyst for a Three-Component Synthesis of 1,4-Dihydropyridines under Solvent-Free Conditions

Biswanath Das; Kanaparthy Suneel; Katta Venkateswarlu; Bommena Ravikanth

doi:10.1248/cpb.56.366

Notes

Sulfonic Acid Functionalized Silica: An Efficient Heterogeneous Catalyst for a Three-Component Synthesis of 1,4-Dihydropyridines under Solvent-Free Conditions

Biswanath Das, Kanaparthy Suneel, Katta Venkateswarlu, Bommena Ravikanth

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Keywords: sulfonic acid functionalized silica, multicomponent reaction, 1,4-dihydropyridine, solvent-free condition

JOURNAL FREE ACCESS

2008 Volume 56 Issue 3 Pages 366-368

DOI https://doi.org/10.1248/cpb.56.366

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Abstract

Sulfonic acid functionalized silica catalyzed the three-component reaction of aromatic amines, α,β-unsaturated aldehydes and β-keto esters forming the corresponding 1,4-dihydropyridines in short reaction times and in high yields.

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