α-Glucosidase Inhibitors Ellagic Acid Derivatives with Immunoinhibitory Properties from Terminalia superba

Abstract

Fractionation of stem barks of Terminalia superba yielded two new ellagic acid derivatives, 3,4′-di-O-methylellagic acid 3′-O-β-D-xylopyranoside (1) and 4′-O-galloy-3,3′-di-O-methylellagic acid 4-O-β-D-xylopyranoside (2) together with known 3,3′-di-O-methylellagic acid, ellagic acid and 3,3′-di-O-methylellagic acid 4′-O-β-D-xylopyranoside. Compounds (1) and (2) showed significant α-glucosidase inhibition activity and possessed significant immunoinhibitory activities with no cytotoxic effects.