Briaexcavatins M—P, Four New Briarane-Related Diterpenoids from Cultured Octocoral Briareum excavatum (Briareidae)

Abstract

Four new briarane-related diterpenoids, designated as briaexcavatins M—P (1—4), were isolated from the cultured octocoral Briareum excavatum. The structures, including the relative configurations of natural products 1—4 were established on the basis of extensive spectral data analysis and by comparison with the spectral data from other known metabolites featuring a briarane carbon skeleton.