New Neolignan Component from Camellia amplexicaulis and Effects on Osteoblast Differentiation

Nguyen Huu Tung; Yan Ding; Eun Mi Choi; Chau Van Minh; Young Ho Kim

doi:10.1248/cpb.57.65

Notes

New Neolignan Component from Camellia amplexicaulis and Effects on Osteoblast Differentiation

Nguyen Huu Tung, Yan Ding, Eun Mi Choi, Chau Van Minh, Young Ho Kim

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Keywords: Camellia amplexicaulis, Theaceae, neolignan, camellioside A, osteoblast differentiation, MC3T3-E1 cell

JOURNAL FREE ACCESS

2009 Volume 57 Issue 1 Pages 65-68

DOI https://doi.org/10.1248/cpb.57.65

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Abstract

A new neolignan named “camellioside A” (1) has been isolated from the leaves and branches of Camellia amplexicaulis, along with seven known glycosides (2—8). Their structures were determined by a variety of spectroscopic analyses. Among them, compounds 2, 3, 4, and 6 significantly (p<0.05) increased the alkaline phosphatase activity and the mineralization of the nodules of the MC3T3-E1 osteoblastic cells compared to those of the control.

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