Four New Triterpenes from Fungus of Fomes officinalis

Abstract

In the previous work we reported five lanostane-type triterpenes from the CHCl₃ soluble fraction of Fomes officinalis. In further study on the isolation of constituents from the CHCl₃ soluble fraction, four new triterpenes, fomefficinic acids F (1), G (2) and fomefficinols A (3), B (4), together with seven known compounds officinalic acid (5), fomlactone A (6), fomlactone B (7), fomlactone C (8), laricinolic acid (9), ergosterol (10), ergota-7,22,dien-3β-ol (11) were isolated. The structures of new compounds were determined by spectroscopic analyses and chemical methods including NMR spectroscopic techniques (¹³C, ¹H, heteronuclear multiple quantum coherence (HMQC), heteronuclear multiple bonding correlation (HMBC), correlation spectroscopy (COSY) and nuclear Overhauser effect spectroscopy (NOESY)).