Thermal Cyclization of Nonconjugated Aryl–Yne–Carbodiimide Furnishing a Dibenzonaphthyridine Derivative

Abstract

The reagent-free C²–C⁷ thermal cyclization of a nonconjugated aryl–yne–carbodiimide yielded a dibenzo[b,g][1,8]naphthyridine derivative, whose congeners are known to possess fascinating pharmacological properties. This is the first heteroaromatic compound prepared by the thermal cycloaromatization of “nonconjugated” aryl–ynes.