Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Novel Bile Acids from Bear Bile Powder and Bile of Geese
Dan BiXing-Yun ChaiYue-Lin SongYu LeiPeng-Fei Tu
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2009 Volume 57 Issue 5 Pages 528-531

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Abstract
Two new bile acids, tauroselocholic acid (1) and tauroansocholic acid (2), a new natural bile acid, cygnocholic acid (3) were respectively isolated from bear bile powder Selenaretos thibetanus CUVIER and bile of geese Anser anser domesticus, together with seven known compounds. By spectrum analysis of MS, 1D and 2D NMR, the structures of the new compounds were elucidated as 3α,7α,9α-trihydroxy-5β-cholan-24-oic acid N-[2-sulfoethyl] amide (1), 3α,5,7α-trihydroxy-5β-cholan-24-oic acid N-[2-sulfoethyl] amide (2) and 3α,7α,15α-trihydroxy-5β-cholan-24-oic acid (3).
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© 2009 The Pharmaceutical Society of Japan
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