Efficient Synthesis of p-Quinols Using Catalytic Hypervalent Iodine Oxidation of 4-Arylphenols with 4-Iodophenoxyacetic Acid and Oxone®

Takayuki Yakura; Masanori Omoto

doi:10.1248/cpb.57.643

Communicatins to the Editor

Efficient Synthesis of p-Quinols Using Catalytic Hypervalent Iodine Oxidation of 4-Arylphenols with 4-Iodophenoxyacetic Acid and Oxone^®

Takayuki Yakura, Masanori Omoto

著者情報

キーワード: p-quinol, 4-iodophenoxyacetic acid, Oxone^®, catalytic hypervalent iodine oxidation, 4-arylphenol

ジャーナルフリー

2009 年 57 巻 6 号 p. 643-645

DOI https://doi.org/10.1248/cpb.57.643

詳細

抄録

Efficient synthesis of p-quinols (2) using catalytic hypervalent iodine oxidation of 4-arylphenols (1) with 4-iodophenoxyacetic acid (3) and Oxone^® was developed. Reaction of 1 with a catalytic amount of 3 in the presence of Oxone^® as a co-oxidant in tetrahydrofuran or 1,4-dioxane–water gave the corresponding 2 in excellent yields.

責任著者(Corresponding author)

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