Delaumonones A and B, New Antiplasmodial Quassinoids from Laumoniera bruceadelpha

Shiori Oshimi; Aki Takasaki; Yusuke Hirasawa; Takahiro Hosoya; Khalijah Awang; A. Hamid A. Hadi; Wiwied Ekasari; Aty Widyawaruyanti; Hiroshi Morita

doi:10.1248/cpb.57.867

Notes

Delaumonones A and B, New Antiplasmodial Quassinoids from Laumoniera bruceadelpha

Shiori Oshimi, Aki Takasaki, Yusuke Hirasawa, Takahiro Hosoya, Khalijah Awang, A. Hamid A. Hadi, Wiwied Ekasari, Aty Widyawaruyanti, Hiroshi Morita

著者情報

Shiori Oshimi
Faculty of Pharmaceutical Sciences, Hoshi University
Aki Takasaki
Faculty of Pharmaceutical Sciences, Hoshi University
Yusuke Hirasawa
Faculty of Pharmaceutical Sciences, Hoshi University
Takahiro Hosoya
Faculty of Pharmaceutical Sciences, Hoshi University
Khalijah Awang
Department of Chemistry, Faculty of Science, University of Malaya
A. Hamid A. Hadi
Department of Chemistry, Faculty of Science, University of Malaya
Wiwied Ekasari
Faculty of Pharmacy, Airlangga University
Aty Widyawaruyanti
Faculty of Pharmacy, Airlangga University
Hiroshi Morita
Faculty of Pharmaceutical Sciences, Hoshi University

キーワード: quassinoid, delaumonone, antimalarial activity, Laumoniera bruceadelpha

ジャーナルフリー

2009 年 57 巻 8 号 p. 867-869

DOI https://doi.org/10.1248/cpb.57.867

詳細

抄録

New quassinoids, delaumonones A (1) and B (2) have been isolated from the bark of Laumoniera bruceadelpha NOOTEBOOM (Simaroubaceae) and the structures were elucidated by 2D NMR analysis and a chemical correlation. Delaumonones showed an antimalarial activity against Plasmodium falciparum.

責任著者(Corresponding author)

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