Ceramide and Cerebroside from the Stem Bark of Ficus mucuso (Moraceae)

Jean Jules Kezetas Bankeu; Sufyan Awad Alkarim Mustafa; Anar Sahib Gojayev; Bruno Djakou Lenta; Didérot Tchamo Noungoué; Silvère Augustin Ngouela; Khalid Asaad; Mohammed Iqbal Choudhary; Sean Prigge; Akif Alekper Guliyev; Augustin Ephrem Nkengfack; Etienne Tsamo; Muhammad Shaiq Ali

doi:10.1248/cpb.58.1661

Notes

Ceramide and Cerebroside from the Stem Bark of Ficus mucuso (Moraceae)

Jean Jules Kezetas Bankeu, Sufyan Awad Alkarim Mustafa, Anar Sahib Gojayev, Bruno Djakou Lenta, Didérot Tchamo Noungoué, Silvère Augustin Ngouela, Khalid Asaad, Mohammed Iqbal Choudhary, Sean Prigge, Akif Alekper Guliyev, Augustin Ephrem Nkengfack, Etienne Tsamo, Muhammad Shaiq Ali

Author information

Jean Jules Kezetas Bankeu
Department of Organic Chemistry, Faculty of Science, TWAS Research Unit of University of Yaounde I
International Center for Chemical and Biological Sciences, University of Karachi
Sufyan Awad Alkarim Mustafa
Medical Biochemistry Research Unit, Medicinal and Aromatic Plants Research Institute, National Center for Research, Sudan
International Center for Chemical and Biological Sciences, University of Karachi
Anar Sahib Gojayev
Biochemistry and Biotechnology Department, Biology Faculty, Baku State University
Bruno Djakou Lenta
Higher Teacher's Training College, University of Yaounde I
Didérot Tchamo Noungoué
Department of Organic Chemistry, Faculty of Science, TWAS Research Unit of University of Yaounde I
Silvère Augustin Ngouela
Department of Organic Chemistry, Faculty of Science, TWAS Research Unit of University of Yaounde I
Khalid Asaad
Medical Biochemistry Research Unit, Medicinal and Aromatic Plants Research Institute, National Center for Research, Sudan
Mohammed Iqbal Choudhary
International Center for Chemical and Biological Sciences, University of Karachi
Sean Prigge
Department of Microbiology and Molecular Immunology, The Bloomberg School of Public Health, Johns Hopkins University
Akif Alekper Guliyev
Biochemistry and Biotechnology Department, Biology Faculty, Baku State University
Augustin Ephrem Nkengfack
Department of Organic Chemistry, Faculty of Science, TWAS Research Unit of University of Yaounde I
Etienne Tsamo
Department of Organic Chemistry, Faculty of Science, TWAS Research Unit of University of Yaounde I
Muhammad Shaiq Ali
International Center for Chemical and Biological Sciences, University of Karachi

Keywords: Ficus mucuso, Moraceae, sphingolipid, mucusamide, mucusoside

JOURNAL FREE ACCESS

2010 Volume 58 Issue 12 Pages 1661-1665

DOI https://doi.org/10.1248/cpb.58.1661

Details

Abstract

Two new sphingolipids mucusamide (1) and mucusoside (2) have been isolated from methanol soluble part of the stem bark of Ficus mucuso WELW., together with fifteen known secondary metabolites including cellobiosylsterol (3), β-sitosterol (4), stigmasterol (5), β-sitosterol 3-O-β-D-glucopyranoside (6), lupeol acetate (7), ursolic acid (8), procatechuic acid (9), 2-methyl-5,7-dihydroxychromone 8-C-β-D-glucoside (10), apigenin (11), (−)-epicatechin (12), (+)-catechin (13), N-benzoyl-L-phenylalanilol (14), α-acetylamino-phenylpropyl α-benzoylamino-phenylpropionate (15), asperphenamate (16) and bejaminamide (17). Structures of compounds 1 and 2 were elucidated by spectroscopic analysis and chemical methods.

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