Four New ent-Kaurane Diterpenoids from the Fruits of Annona cherimola

Hiroyuki Miyashita; Makiko Nishida; Masafumi Okawa; Toshihiro Nohara; Hitoshi Yoshimitsu

doi:10.1248/cpb.58.765

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Four New ent-Kaurane Diterpenoids from the Fruits of Annona cherimola

Hiroyuki Miyashita, Makiko Nishida, Masafumi Okawa, Toshihiro Nohara, Hitoshi Yoshimitsu

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Keywords: Annona cherimola, ent-kaurane, diterpenoid, Annonaceae

JOURNAL FREE ACCESS

2010 Volume 58 Issue 5 Pages 765-768

DOI https://doi.org/10.1248/cpb.58.765

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Abstract

Four new ent-kaurane diterpenoids (16R)-ent-kauran-17,19-diol (1), (16R)-17-hydroxy-ent-kauran-19-oic acid (2), (16S)-17-hydroxy-ent-kauran-19-oic acid (3), and (16R)-17-dimethoxy-ent-kauran-19-oic acid (4) have been isolated from the fresh fruits of Annona cherimola together with eight known compounds. Their structures are determined on the basis of spectroscopic data and optical rotation.

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