Larrealignans A and B, Novel Lignan Glycosides from the Aerial Parts of Larrea tridentata

Akihito Yokosuka; Yukiko Matsuo; Maki Jitsuno; Kohei Adachi; Yoshihiro Mimaki

doi:10.1248/cpb.59.1467

Regular Articles

Larrealignans A and B, Novel Lignan Glycosides from the Aerial Parts of Larrea tridentata

Akihito Yokosuka, Yukiko Matsuo, Maki Jitsuno, Kohei Adachi, Yoshihiro Mimaki

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Keywords: lignan, lignan glycoside, Larrea tridentata, Zygophyllaceae, cytotoxic activity

JOURNAL FREE ACCESS

2011 Volume 59 Issue 12 Pages 1467-1470

DOI https://doi.org/10.1248/cpb.59.1467

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Abstract

Two new lignan glycosides, named larrealignans A (1) and B (2), and a known lignan (3) were isolated from the aerial parts of Larrea tridentata (Zygophyllaceae). The structures of 1 and 2 were determined on the basis of spectroscopic analysis and the results of hydrolytic cleavage. The isolated compounds (1—3) and aglycones (1a, 2a) of 1 and 2 were evaluated for their cytotoxic activities against HL-60 human leukemia cells.

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