New Triterpenoid Saponins from Fruit Specimens of Panax japonicus Collected in Toyama Prefecture and Hokkaido (2)

Abstract

Four new dammarane-type triterpenoid saponins, chikusetsusaponin FT₁ (1), chikusetsusaponin FT₂ (2), chikusetsusaponin FT₃ (3), chikusetsusaponin FT₄ (4), and six known triterpenoid saponins, chikusetsusaponin FK₄ (8), chikusetsusaponin FK₅ (9), chikusetsusaponin FK₂ (10), chikusetsusaponin FK₃ (11), chikusetsusaponin LN₄ (12), and chikusetsusaponin IVa (14), were isolated from the fruits of Panax japonicus C. A. MEYER, collected in Toyama prefecture, Japan, and five new dammarane-type triterpenoid saponins, chikusetsusaponin FT₁ (1), chikusetsusaponin FT₃ (3), chikusetsusaponin FT₄ (4), chikusetsusaponin FH₁ (5), chikusetsusaponin FH₂ (6), and eight known triterpenoid saponins, ginsenoside Re (7), chikusetsusaponin FK₅ (9), chikusetsusaponin FK₂ (10), chikusetsusaponin FK₃ (11), chikusetsusaponin LN₄ (12), 28-desglucosylchikusetsusaponin IVa (13), chikusetsusaponin IVa (14), and chikusetsusaponin V (15), were isolated from the fruits of P. japonicus C. A. MEYER, collected in Hokkaido, Japan. The structures of new chikusetsusaponins were elucidated on the basis of chemical and physicochemical evidences.