Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Antioxidant and Anti-nitric Oxide Components from Quercus glauca
Chien-Chang ShenKun-Yuan HongJennifer ChenLi-Jie ZhangZhi-Hu LinHung-Tse HuangHui-Ling ChengYao-Haur Kuo
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2012 年 60 巻 7 号 p. 924-929

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From the ethanolic extract of Quercus glauca, two new lignans, (+)-5′-methoxyisolariciresinol-9′-O-α-L-rhamnopyranoside (1) and (7R,8S)-dihydrodehydrodiconiferyl alcohol 4-β-D-xyloside (2), along with fourteen known compounds including four lignanoids (36), five triterpenoids (711), two flavonoids (12, 13), two aromatics (14, 15), and one steroid (16) were isolated. The structures of the new compounds were elucidated on the basis of spectroscopic analysis. Moreover, compounds 9 and 14 strongly inhibited nitric oxide (NO) production with IC50 values of 8.25 and 14.04 µM, respectively, and compounds 1, 46, 14, and 15 showed moderate antioxidant activities.

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© 2012 The Pharmaceutical Society of Japan
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