Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Special Collection of Papers: Regular Articles
Conversion of Vindoline into 11-Mesyloxytabersonine
Yuki Han-ya, Tomohiko Inui, Satoshi Yokoshima, Hidetoshi Tokuyama, Tohru Fukuyama
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Keywords: alkaloid, indole, natural product, vindoline, tabersonine
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2016 Volume 64 Issue 7 Pages 800-804

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Abstract

Conversion of readily available vindoline to 11-mesyloxytabersonine, a versatile synthetic intermediate for indole alkaloids, has been achieved by a 9-step sequence in 39% overall yield.

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© 2016 The Pharmaceutical Society of Japan
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