Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
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Solid-Phase Modular Synthesis of Park Nucleotide and Lipids I and II Analogues
Akira KatsuyamaKousuke SatoFumika YakushijiTakanori MatsumaruSatoshi Ichikawa
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2018 年 66 巻 1 号 p. 84-95

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A solid-phase synthesis of Park nucleotide as well as lipids I and II analogues, which is applicable to the synthesis of a range of analogues, is described in this work. This technique allows highly functionalized macromolecules to be modularly labeled. Multiple steps are used in a short time (4 d) with a single purification step to synthesize the molecules by solid-phase synthesis.

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© 2018 The Pharmaceutical Society of Japan
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