Communication to the Editor
Photoinduced Reductive Dehalogenation of Phenacyl Bromides with Pyridoxal 5′-Phosphate
2023 年 71 巻 9 号 p. 675-677
詳細
2023 年 71 巻 9 号 p. 675-677
We describe the photoinduced reductive debromination of phenacyl bromides using pyridoxal 5′-phosphate (PLP). The reaction requires irradiation with cyan or blue light in an anaerobic atmosphere. Mechanistic analysis reveals the formation of the phenacyl radical as an intermediate in the reaction, implying a single electron transfer to phenacyl bromides from a PLP-derived species resulting from excitation by illumination.
