Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
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Comparison of Non-ephedrine Constituents from Ephedra Plants Cultivated in Japan
Kengo HayashiYuki MiyaoHina MatsuiTakao YamauraKen TanakaMariko BabaHiroaki Hayashi
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Supplementary material

2024 Volume 72 Issue 4 Pages 385-388

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Abstract

Ephedra plants, the main components of which are ephedrine alkaloids, are used as traditional medicines in Eastern Asian countries. In this study, we isolated non-ephedrine constituents from various Ephedra plant species cultivated in Japan. HPLC analysis suggested that kynurenic acid and its derivatives accumulated in a wide range of Ephedra plant species. Furthermore, a large amount of (2R,3S)-O-benzoyl isocitrate has been isolated from E. intermedia. This study suggests that Ephedra plants have diverse non-ephedrine constituents.

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Published by The Pharmaceutical Society of Japan

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