Pharmaceutical Bulletin
Online ISSN : 1881-1345
Print ISSN : 0369-9471
ISSN-L : 0369-9471
Benzylamine誘導体の分解(第4報)ベンチルカチオンの芳香性置換反応について その1
砂川 玄俊
著者情報
ジャーナル フリー

1955 年 3 巻 2 号 p. 116-124

詳細
抄録
The compounds of the general formula [chemical formula], where R is a substituent with +M effect in the ortho- or para-position of -CH2-, R' is H or alky l (or aminoalkyl) group, and R" is an aromatic residue, when heated with dilute hydrochloric acid, are cleaved first into benzyl alcohol and an aromatic amine. When the reaction proceeds further, a diphenylmethane compounds are formed by the aromatic electrophilic substitution of the following order : [chemical formula] In some cases, the aromatic amine liberated in the first stage of the reaction takes part in the second stage of the reaction which proceeds in the following order, as had earlier been recognized.
著者関連情報
© 社団法人 日本薬学会
前の記事 次の記事
feedback
Top