Abstract
1) Dehydroaroyla cetic acids were directly obtained by Friedel-Crafts reaction of triacetic acid lactone (TAL) and aroyl chloride in the presence of an excess of aluminum chloride. They were also derived from the corresponding 4-benzoates of TAL by Fries rearrangement using the excessive aluminum chloride.
2) The monobenzoate of TAL synthesized by the usual method as also reported in the previous reports was definitely shown to be the 4-benzoate rather than the 2-benzoate.
3) None of these new compounds was superior to DHA in the activity against Bacillus subtilis, Staphylococcus aureus, Escherichia coli B and Aspergillus niger in vitro.
