Abstract
It has been found that the Friedel-Crafts reaction of 3-iodoanisole with acetyl chloride yielded, contrary to Oki's report, four products, 2'-hydroxy-4'-iodo-, 2'-iodo-4'-hydroxy, 2'-iodo-4'-methoxy-, and 2'-methoxy-4'-iodoacetophenone
The Ullmann condensation of 2'-iodo-4'-methoxyacetophenone with methyl 2-bromoor2-iodo-veratrate, followed by hydrolysis, gave, in a poor yield, 2'-acetyl-5, 5'6-trimethoxy-2-biphenylcarboxylic acid which was characterized as its oxime as well as its methyl ester.
