Studies on Pyridazine Derivatives. II. Synthesis of 6-Substituted 3-(p-Nitrophenyl)-, 3-(p-Tolyl)-and 3-(p-Aminomethylphenyl) sulfonamidopyridazines

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In order to find antimicrobial agents, compounds of 6-substituted 3-(p-nitrophenylsulfonamido) pyridazine, 6-substituted 3-(p-tolylsulfonamido) pyridazine and 6-substituted 3-(p-aminomethylphenylsulfonamido) pyridazine were synthesized and screened as to their activities on Staph. aureus and E. coli, but any of them was found uneffective.