Abstract
Pyridazine N-oxide derivatives have been studied by NMR spectroscopy. In all cases the spectra were simple patterns, which could be easily assigned by first order treatments. In order to obtain a complete assignment of the ring proton signals, a number of pyridazine N-oxide derivatives were examined, and the structures determined from the results are consistent with the dipole moment studies. Analysis of N-oxidation reaction mixtures of pyridazine derivatives was performed by NMR spectroscopy. Substituent effects on the chemical shifts are discussed in relation to the other aromatic ring systems. The electronic distribution of pyridazine N-oxide and diamagnetic anisotropy effect of N-O group are also discussed briefly.
