Application of Nuclear Magnetic Resonance to Stereochemistry. II. Determination of the Conformation of Hydroxyl Groups by Nuclear Magnetic Resonance ; Androst-4-en-3-one and Pregn-4-en-3-one Series.

Abstract

It is shown from the nuclear magnetic resonance data of 23 kinds of androst-4-ene and pregn-4-ene derivatives that nuclear magnetic resonance can be applied to determination of the position and the configuration of unknown hydroxyl groups in steroidal molecules.