Potential Anti-cancer Agents. XI. Synthesis of 4- and 5-Azidopyridazine 1-Oxide.
1963 年 11 巻 8 号 p. 1059-1064
詳細
1963 年 11 巻 8 号 p. 1059-1064
Reaction of 3, 4, 5-trichloropyridazine (IV) with sodium methoxide was examined. 4-Azidopyridazine 1-oxide (XVII) and 5-azidopyridazine 1-oxide (XXI) were synthesized from corresponding hydrazino compounds (XIV, XX) with nitrous acid, and XVII was also derived from 4-chloropyridazine 1-oxide (XIII) with sodium azide.
