Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Antitumor Substances. III. Syntheses of Bis(methanesulphonylthio)alkanes
林 清五郎植木 寛原野 誠子小宮 順子井山 駿原野 一誠宮田 勝昭新形 邦宏米村 嘉郎
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1964 年 12 巻 11 号 p. 1271-1276

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Dimethanesulphonylthioalkanes and analogous compounds were synthesized by the reaction of corresponding sodium thiosulphonate and appropriate dibromide to test the carcinostatic activity compaed with Myleran. It was found that some of these compounds inhibited pronouncedly the growth of the solid tumor produced by Ehrlich ascites carcinoma cells.

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© The Pharmaceutical Society of Japan
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