Abstract
The nitration of 3-methyl-, 3, 6-dimethyl-, and 3-methoxypyridazine 1-oxide with benzoyl chloride-silver nitrate afforded their corresponding 5-nitro derivatives, while in the reaction of 3, 6-dimethoxypyridazine 1-oxide with the same reagents, no nitro compound was detected but 1-hydroxy-3-methoxy-6 (1H)-pyridazinone and its benzoyl derivative were produced. Some nucleophilic substitution reactions related to 5-nitropyridazine 1-oxides obtained here, were described.
