Abstract
Thioamides have been cyclized in good yield to the corresponding 1-substituted 3, 4-dihydroisoquinoline under the normal Bischler-Napieralski reaction conditions which are generally used to cyclize acid amides. Phosphorus pentasulfide has been effectively used as a condensing agent in the Bischler-Napieralski reaction to get 1-substituted-3, 4-dihydroquinoline from both thioamides as well as normal acid amides.
