Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Synthesis of Nitro Compounds by Means of Oxidation of Acylamino Compounds. X. Reinvestigation of Reaction Conditions of Oxidation of Acylamino Compounds to Nitro Compounds.
伊藤 晴之
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1964 年 12 巻 3 号 p. 329-337

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Acylarylamino compounds having chloro or methoxyl group at meta-or para-position of benzene ring were oxidized with hydrogen peroxide in varied conditions. In the case of introduction of electron-attracting group, yields of nitro compounds were fairly good and at the same time, considerable amounts of the starting materials were recovered, while, in the case of electron-releasing group, yields of nitro compounds were poor and almost none of the starting materials was recovered. Reasonable explanations of these phenomena were discussed.
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© The Pharmaceutical Society of Japan
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