Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Nucleosides and Nucleotides. VII. Synthesis of 2-Amino-6-substituted-9-β-D-ribofuranosylpurines
内藤 武男上野 勝次郎石川 文義
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1964 年 12 巻 8 号 p. 951-954

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In the 2-amino-6-substituted-9-β-D-ribofuranosylpurines series, 6-hydrazino (VI), 6-methylhydrazino (VIII), 6-hydroxylamino (VII), 6-methylamino (X), and 6-dimethylamino (XI) derivatives were synthesized by condensation of 6-alkylthioguanosines with respective amines. VI and VII were reduced with Raney nickel to 2, 6-diamino derivative (IX). Similarly, VIII was also reduced with Raney nickel to X.
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