Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Isoxazoles. XVI. The Reaction of Nitrous Acid on 5-Amino-3, 4-dialkylisoxazoles
加納 日出夫足達 郁夫山崎 瑛子
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1964 年 12 巻 9 号 p. 1021-1024

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The reaction products of nitrous acid on 5-amino-3, 4-dialkylisoxazoles (Ia, b, c) has been formulated as 4-(3, 4-dialkyl-5-isoxazolyl)azo-3, 4-dialkyl-5(4H)-isoxazolones (IVa, b, c) rather than the azoxy structure (II) which was originally proposed by Hanriot. To gain insight into this reaction mechanism, the behavior of o-, m-, and p-nitrobenzenediazonium chlorides on Ia has been also investigated.
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© The Pharmaceutical Society of Japan
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