Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on the Structure of Itaconitin. IV. The Reactions of Itaconitin and Anhydroitaconitin
仲嶋 正一木下 広野柴田 承二
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1965 年 13 巻 1 号 p. 58-64

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The ozonolysis of anhydroitaconitin which was prepared from itaconitin by the action of acetic or propionic anhydride followed by hydrolysis, yielded, 2, 4-cresotaldehyde liberating acetaldehyde and carbon dioxide. Treatment of the same substance with nitric acid afforded 2, 4, 6-trinitro-m-cresol. These and other experimental results showed that the anhydroitaconitin was an aromatic compound having a m-cresyl grouping with an adjacent ethylenic linkage. The catalytic hydrogenation of anhydroitaconitin in acetone gave dihydroanhydroitaconitin, whereas in alkali gave a carboxylic acid, C14H18O5.
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© The Pharmaceutical Society of Japan
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