Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Chemical Transmission in Taste Fibre Endings. III. The Action of Acetylcholine and 2-Dimethylaminoethanol on the Taste Fibre Endings
Kakuichi SakaiHikaru Ozawa
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1965 Volume 13 Issue 12 Pages 1440-1444

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Abstract
Taste substances were administered to the frogs tongue treated with acetylcholine (ACh) in 10% propylene glycol solution and 2-dimethylaminoethanol (DMAE) which is considered to be precursor of ACh in animal body, and the changes in the sense of taste were studied by electrophysiological method. As a result, it was found that sense of taste was enhaced after trastment of the tongue with ACh as compared with before treatment. In addition, a phenomenon of sustained action of sense of taste was observed with DMAE. This suggests that as ACh-like substance may play an important role in the transmission of sense of taste.
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© The Pharmaceutical Society of Japan
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