Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Analgesics of Aniline Series. II. Preparation and Properties of N-Alkyl or N, N-Dialkyl 3-(N'-Acyl- or N'-Benzyl-substituted anilino) propionamide Series and N-Alkyl or N, N-Dialkyl 3-(Substituted anilino) propylamine Series
高村 圭一, 塩屋 明利, 源 勝麿, 山本 忠広, 吉満 亮人, 新田 義博
著者情報
ジャーナル フリー

1965 年 13 巻 2 号 p. 205-210

詳細
抄録
N-Alkyl or N, N-dialkyl 3-(N'-acyl-, N'-alkyl- or N'-benzylsubstituted anilino)propionamide derivatives were prepared from corresponding N-alkyl or N, N-dialkyl 3-(substituted anilino) propionamides by treating with acid anhydride, alkylhalide, or formaldehyde, formic acid and benzyl chloride, respectively. N, N-Dialkyl 3-(substituted anilino) propylamines were also prepared by condensation of 3-(substituted anilino) propyl chlorides with secondary amines. N, N-Dialkyl 3-(N'-acyl-substituted anilino) propylamines were obtained by treatment of 3-(substituted anilino) propylamines with acid anhydrides. Some of these compounds were found to possess analgetic activities.
著者関連情報
© The Pharmaceutical Society of Japan
前の記事 次の記事
feedback
Top