Abstract
Reactions between 2-aminotropone derivatives and dialkyl sulfates were examined. Methylation sodium salt of 2-aminotropone with dimethyl sulfate resulted in N-methylation yielding 2-methylaminotropone (III). On the other hand, the direct methylation of 2-aminotropone (I) with dimethyl sulfate resulted in O-methylation yielding 2-methoxytroponeimine (V). Troponeimines listed in Table I were prepared by the direct alkylation of 2-aminotropone derivatives with dialkyl sulfates. In these preparations, sulfonates listed in Table II were also obtained.
