Abstract
Sixteen nitrofurylvinylquinoline compounds were examined for their phage inducing activity on E. coli K 12 (λ), a lysogenic strain. Excepting compounds having -COOH, -CONH2, -NO2, or -Br on the quinoline nucleus, they had phage inducing ability. The compound, 4, 6-Diamino-2Q-ran HCl was the strongest among them and its activity was twice as strong as that of Mitomycin C, a drug for cancer. It is a notable fact that the tested nitrofurylvinylquinoline compounds which have an inducing activity in lysogenic bacteria exhibit, with one exception, an antitumor effect on bearing Ehrlich ascites carcinoma.
