Abstract
5, 8-Dichloropyrido[2, 3-d]pyridazine was prepared and its reactions with nucleophiles, such as hydroxide, alkoxide, thiourea, ammonia, anilines, and hydrazine were carried out. Monosubstituted isomeric products were isolated, and their isomeric structures were determined by converting them into known structures. Monohydrazino derivatives were cyclized with acid or acid anhydride into triazolo derivatives.