Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Pyridazine Derivatives. VIII. Pyrido[2, 3-d]pyridazines. I.
Yoshihiro NittaIkutoshi MatsuuraFumio Yoneda
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1965 Volume 13 Issue 5 Pages 586-593

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Abstract
5, 8-Dichloropyrido[2, 3-d]pyridazine was prepared and its reactions with nucleophiles, such as hydroxide, alkoxide, thiourea, ammonia, anilines, and hydrazine were carried out. Monosubstituted isomeric products were isolated, and their isomeric structures were determined by converting them into known structures. Monohydrazino derivatives were cyclized with acid or acid anhydride into triazolo derivatives.
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© The Pharmaceutical Society of Japan
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